6-Jul-2025
新型多模态纳米药物通过增敏铁死亡和重塑肿瘤微环境促进膀胱癌免疫治疗疗效
ResearchPeer-Reviewed Publication
中山大学孙逸仙纪念医院陈旭研究员团队研发出一款以二价铁离子、表没食子儿茶素没食子酸酯(EGCG)及铁死亡诱导剂RSL3为原料的新型多模态纳米药物Fe-EGCG@RSL3,以增敏铁死亡从而促进膀胱癌免疫治疗疗效。该研究以题为“A Multifunctional Fe-EGCG@RSL3 Nanomedicine Synergizes Ferroptosis Induction and Tumor Microenvironment Remodeling for Enhanced Bladder Cancer Immunotherapy”发表在Research期刊上。
- Journal
- Research
- Funder
- National Natural Science Foundation of China, Guangdong Basic and Applied Basic Research Foundation, Science and Technology Program of Guangzhou, Fundamental Research Funds for the Central Universities, Sun Yat-sen University, Guangdong Provincial Clinical Research Centre for Urological Diseases, Guangdong Science and Technology Department, China Postdoctoral Science Foundation