APHA Executive Director Yvette Raphael receives Mani L. Bhaumik Breakthrough of the Year Award
Advocates for the Prevention of HIV in AfricaGrant and Award Announcement
Advocates for the Prevention of HIV in Africa (APHA) announces that its co-founder and Executive Director, Yvette Raphael, has been awarded the prestigious Mani L. Bhaumik Breakthrough of the Year Award for her pivotal role in advancing HIV prevention through the development and testing of Lenacapavir, the revolutionary long-lasting HIV prevention drug.
The award, established by the American Association for the Advancement of Science (AAAS), recognizes three key contributors to this medical breakthrough: Wesley Sundquist (University of Utah), who provided foundational scientific research; Moupali Das (Gilead Sciences), who championed clinical development; and Yvette Raphael, who ensured clinical trials were inclusive, ethical, and community-centered.
As Chair of the PURPOSE 1 Advisory Board, Raphael transformed clinical trial practices by insisting on the inclusion of young women, adolescents, and pregnant women in sub-Saharan Africa. This inclusive approach led to groundbreaking results: 100% efficacy in preventing HIV infections with just two injections per year.
Raphael's leadership exemplifies how community engagement improves scientific outcomes. While celebrating this significant breakthrough, APHA acknowledges that more research is required to find an HIV vaccine and remains committed to ensuring these innovations become accessible to all who need them.
The organization recognizes that Raphael's work has required support from her Board, colleagues, program partners, fellow advocates, researchers, and communities, demonstrating that when scientists, pharmaceutical companies, and community advocates collaborate with mutual respect, extraordinary progress becomes possible.