20-Aug-2025
Breast tumors tunnel into fat cells to fuel up. Can we stop them?
University of California - San FranciscoPeer-Reviewed Publication
When triple-negative breast cancer grows, the fat cells around it seem to shrink.
UCSF researchers have discovered that the cells of these tumors, which are among the deadliest types of breast cancer, build molecular tunnels, called gap junctions, into nearby fat cells. The tumor cells then send instructions that trigger the fat cells to release stores of energy that could feed the cancer.
- Journal
- Nature Communications
- Funder
- U.S. Department of Defense, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, Atwater Foundation, Bechtle Family Foundation, Breast Cancer Research Fund, Subramanian Breast Cancer Support Fund, European Molecular Biology Organization, U.S. Department of Defense