While we know obstacles on the beach can slow down hatchlings and put them at risk, little research has focused on the impact of sargassum. A new study of loggerhead, leatherback and green hatchlings finds that all three species took significantly longer to complete their crawl when sargassum was present. The time it took to climb up and over the seaweed piles was the primary reason. Even small piles delayed their crawl, with many flipping over and failing to climb the seaweed in time.

This study investigates the susceptibility of African spiny mice (Acomys dimidiatus) to carcinogenesis induced by DMBA/TPA, a common two-stage chemical carcinogenesis model. The research reveals that despite their high regenerative capacity, Acomys exhibits resistance to skin carcinogenesis, showing delayed tumor formation and a distinct benign tumor profile compared to C57BL/6 mice. The study highlights the role of enhanced immune response, higher apoptosis, and inhibition of Wnt/β-catenin signaling in conferring this resistance.

EZH2, the catalytic core of the Polycomb Repressive Complex 2 (PRC2), silences gene expression through H3K27me3 modification and is emerging as a master epigenetic regulator beyond cancer. The review “EZH2 in Non-Cancerous Diseases: Expanding Horizons” by Prof. Lixiang Xue's team, published in Protein & Cell, systematically uncovers EZH2’s multifaceted roles in autoimmune, fibrotic, metabolic, and neurological diseases. The authors propose a CDE3 therapeutic model to advance targeted epigenetic therapy in chronic diseases.