About The Study: Extended low-intensity anticoagulation with apixaban was associated with a reduction in symptomatic superficial vein thrombosis (SuVT) in patients with provoked venous thromboembolism with enduring risk factors for recurrence. Further randomized clinical trials specifically focused on SuVT are needed to ascertain optimal antithrombotic strategies in broader populations at risk of SuVT.

About The Study: After multivariable adjustment, serum neurofilament light chain (sNfL) levels were associated with a broad range of adverse cardiovascular events and mortality in patients with atrial fibrillation (AF). Serum NfL may serve as a biomarker of cardiovascular risk in patients with AF.

About The Study: The results of this post hoc analysis of the Finerenone Trial to Investigate the Efficacy and Safety Superior to Placebo in Patients With Heart Failure (FINEARTS-HF) randomized clinical trial reveal that in this contemporary heart failure with mildly reduced ejection fraction or heart failure with preserved ejection fraction cohort, sudden death was preceded by modest worsening of symptoms, declining quality of life, and rising natriuretic peptide levels, suggesting many of these events may not have been entirely sudden. However, similar deterioration preceding other modes of death suggests limited specificity for sudden death.

About The Article: This Viewpoint discusses obesity prevention and control as an underestimated and underutilized strategy in the prevention of numerous cancers.