Researchers at Hiroshima University have developed a new tool to quickly and accurately map fungal gene functions, even for species that have never been studied before.

Researchers identified the tegmentum in the midbrain as an ‘integration center’ of fish. The area receives visual information from the eyes that is combined with color information detected by the pineal organ—the ‘third eye.’ These inputs are integrated to control how fish orient themselves in the water.

Understanding how representative currently known proteins are of the overall potential diversity can help inform strategies for a wide range of applications, including therapeutic, biocatalysis, or biomaterials development. Published in PNAS, an OIST-led international team investigated the relationship between protein evolution and sequence space, identifying the limiting factors behind protein diversification. Their findings reinforce theories of DNA recombination as a driving force of ancestral protein formation and highlight the limitations of many cutting-edge AI protein design methods.

From smartphones to supercomputers, almost all our daily electronics run on the flow of "electron charge." But did you know? Electrons have another interesting property called "spin." In this feature, we sit down with Associate Professor Yamashita, a young researcher exploring this mysterious "electron spin" to create next-generation, ultra-high-performance devices. Join us as we dive into the world of Spintronics—the future of technology—and hear his inspiring message for the students who will lead the way!

Concrete harbors distinct microbial zones whose signatures survive the heat of routine core sampling, a discovery researchers say could one day put structural health diagnostics within reach of general maintenance staff and even residents.

Preterm birth is a major cause of neonatal illness and death, especially among women with a history of premature delivery. Researchers in Japan explored whether taking probiotics early in pregnancy could help reduce the risk of spontaneous preterm delivery (sPTD). In a multicenter clinical trial, women who consumed probiotics containing Clostridium butyricum showed lower recurrence rates compared with national averages, suggesting that probiotic therapy may offer a simple strategy to help prevent premature births.

Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks. Now, researchers from Japan have identified the enzyme NOX-1 as a key molecular target to prolong ketamine’s antidepressant effects. Their findings shed light on key molecular and brain circuit mechanisms and point to new research directions for developing longer-lasting treatments for depression.

Immunoglobulin A (IgA) nephropathy results from the accumulation of IgA-containing immune complexes (IgA-ICs) and aberrant IgA antibodies in the glomerular mesangium. Now, researchers have found that complement pathway proteins are involved in the formation of these complexes. One such protein, complement factor H-related protein 1, is overexpressed in the glomeruli and IgA-ICs isolated from patients and could serve as a biomarker for disease susceptibility and progression, as well as a possible target for new therapies.

Grasping and transporting objects is one of the most critical tasks for robots in a variety of fields. This task requires accurate 3D measurement of the objects. However, transparent or specular objects make measurement challenging, reducing grasping success rate. To address this, researchers have developed HEAPGrasp, a new technique that performs 3D measurement of objects using only their silhouettes, thus avoiding dependence on their optical properties. This approach significantly improves grasping success rate of robots.

Researchers, including those from the University of Tokyo, combine various past climate data to investigate the impacts of ancient volcanic eruptions. They explored eruptions in the tropics over the last 1,000 years and found some large eruptions have far-reaching climatic consequences. Preserved tree rings, as well as climate models, show evidence that some monsoon activity is reduced following particularly large tropical eruptions. This research could impact current climate models, eruption simulations, and even influence long-term disaster preparedness given the potential impact eruptions can have on monsoon-dependent crop supplies.