In November 2025, a team led by Dr. Yuting Guo at the University of Chinese Academy of Sciences revealed how mitochondria-ER contact sites (MERCS) decode proteotoxic stress via calcium nanodomain regulation, activating adaptive mitochondrial responses. Published in Protein & Cell, the work proposes new therapeutic avenues for neurodegenerative diseases.

A simple palladium-catalyzed reaction system of C₂H₆-O₂-CO-H₂O that enables the selective oxidation of ethane to acetate acid, has been reported in a recent paper published in National Science Review. In the refined reaction system with the addition of sulfuric acid, it achieves remarkable performance with high ethane conversion of 15.7% and high acetate acid selectivity of 92.1%. The reaction pathway and mechanism are clearly interpreted through kinetic and spectroscopic analyses and supported by theoretical calculations. This study offers a promising pathway for the upgrading and utilization of natural gas under mild conditions.

Preschool-age children are most engaged in pretend play 10-15 minutes after playing begins. In addition, girls exhibit higher organisational skills, according to a study conducted by researchers from SWPS University and Istanbul University-Cerrahpaşa.

A research team at Universidad Carlos III de Madrid (UC3M) has developed technology using advanced machine learning techniques that detects signs of gender violence from paralinguistic characteristics of the voice such as tone, rhythm, and intensity. This innovative method helps to recognize situations of psychological stress or trauma while preserving the privacy of the speakers, which could have major implications for telephone helplines and telemedicine services.

New research from the University of Waterloo suggests that more than creativity is at play. Behind many great melodies, researchers found something surprisingly powerful: symmetry. Their work shows that advanced algebra can reveal deep musical patterns that are not always obvious by ear or even on a written score. 

The findings could help composers better understand what makes melodies work, as the study offers a recipe for generating new melodies that follow specific symmetry rules, opening new creative possibilities for composers and researchers.