Article Highlights
Updates every hour. Last Updated: 23-Jan-2026 08:11 ET (23-Jan-2026 13:11 GMT/UTC)
Stingrays inspire smarter ocean robots
University of California - Riverside- Journal
- Journal of The Royal Society Interface
Crouzon syndrome diagnosed in a knight from the Order of Calatrava, killed in battle over 600 years ago
Universitat Rovira i Virgili- Journal
- Heritage
PolyU research finds frequent Arctic wildfires could cut snow cover by 18 days, impacting global climate and ecology
The Hong Kong Polytechnic University- Journal
- Nature Climate Change
Flies and the hidden drivers of cholera
University of the WitwatersrandNew modelling research from African biostatisticians shows that flies play a far more important role in spreading cholera than previously recognised. While cholera is traditionally associated with contaminated water, the study demonstrates that flies can mechanically transmit the cholera-causing bacterium from contaminated environments to human food, making outbreaks faster and more unpredictable.
The models show that when fly-related transmission factors are high, even small contamination events can trigger explosive outbreaks, likened to sparks igniting dry grass. The findings come as Africa faces its worst cholera outbreak in 25 years, with 300,000 confirmed and suspected cases reported across 20 countries in 2025.
The research also reinforces the importance of vaccination, showing that high coverage can rapidly reduce transmission even before long-term water and sanitation improvements take effect.
- Journal
- Mathematics
Finding the balance: How European societies navigate the tensions in education
ECNU Review of EducationThis feature explores how European education systems negotiate tensions between collective ideals and growing competition. Drawing on studies from Denmark, Sweden, Norway, and Belarus, it examines shadow education, policy debates over equity, culturally grounded early childhood learning, and enduring post-Soviet public institutions. Together, these perspectives reveal education as a social mirror, continuously balancing public good, cultural identity, historical legacy, and individual ambition across diverse European contexts and shared societal values.
Tumor suppressor protein-inspired peptide for siRNA delivery and synergistic cancer therapy
KeAi Communications Co., Ltd.Small interfering RNA (siRNA) has shown promising therapeutic prospects in many major diseases. However, two main reasons limit the application of siRNA: poor endocytosis efficiency and weak endosomal escape ability. Therefore, the development of efficient and safe delivery vectors has always been an important study aspect of RNAi technology. Herein, we designed a self-assembled nanoparticle based on functionalized peptides to deliver siRNA to the down-regulated polo-like kinase 1 (PLK1) gene, which can inhibit tumor cells in the G2 phase. The functional polypeptide consists of cell membrane-penetrating peptide (CPP44) and p16 minimal inhibitory sequence (p16MIS). CPP44 can effectively mediate endocytosis, while p16MIS can inhibit tumor growth in the G1 phase and synergistically promote the apoptosis of tumor cells with siPLK1. In vitro and in vivo studies demonstrate that the developed nanoparticle exhibits high levels of silencing efficiency, antitumor activity, and therapeutic efficacy. Consequently, this study provides a novel approach to cancer treatment by simultaneously disrupting two stages of tumor cell division.
- Journal
- Fundamental Research
- Funder
- National Natural Science Foundation of China, Beijing Nova Program (Interdisciplinary Cooperation Project) from Beijing Municipal Science & Technology Commission, National Key Research & Development Program of China, National Natural Science Foundation of China (NSFC) key project, NSFC international collaboration key project, Science Fund for Creative Research Groups of Nature Science Foundation of Hebei Province, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, Biological and Medical Engineering Core Facilities and Analysis & Testing Center, Beijing Institute of Technology
Achieving impact-buffered compressible batteries through 3D printing-assisted design of negative Poisson's ratio structural electrodes
KeAi Communications Co., Ltd.This study presents a metamaterial-inspired design to develop negative Poisson's ratio (NPR) structural electrodes using a directional freezing 3D printing-assisted strategy. This approach incorporates both macroscopic NPR structures and microscopic directional porous structures, which enhances ion transport, improves compressibility and provides impact resistance, effectively preventing package bulges during compression. Consequently, the electrodes demonstrate a high 50% compressible deformation and recover their original state even after 50 cycles of 25% compression. The 3D-printed lithium iron phosphate cathodes deliver a high average specific capacity of 153 mAh/g over 100 cycles and exhibit outstanding rate capability. Furthermore, the assembled full cell maintains both excellent compressibility and impact-buffered resistance, highlighting its potential applications. This innovative design of NPR metamaterial-structured electrodes provides a universal platform for developing the next generation of impact-buffered, compressible structural batteries.
- Journal
- Fundamental Research
- Funder
- National Key Research and Development Program of China, National Natural Science Foundation of China, Natural Science Foundation of Jiangsu Province, Major Project, Start-up Research Fund of Southeast University, Taihu Lake Innovation Fund for the School of Future Technology of Southeast University
Iron supplementation improves muscle function in a mouse model of muscular dystrophy
Kumamoto UniversityResearchers at Kumamoto University have demonstrated that iron supplementation can significantly alleviate muscle pathology and functional decline in a mouse model of facioscapulohumeral muscular dystrophy (FSHD), a rare genetic muscle disease for which no effective treatment currently exists.
- Journal
- Journal of Clinical Investigation
- Funder
- National Center of Neurology and Psychiatry, Japan Agency for Medical Research and Development, Japan Science and Technology Agency, Japan Society for the Promotion of Science, Ministry of Education, Culture, Sports, Science and Technology, Japan, Takeda Science Foundation, Astellas Foundation for Research on Metabolic Disorders, Kumamoto University
A molecular switch fine-tunes petal size in roses
Nanjing Agricultural University The Academy of SciencePetal size is a defining trait of ornamental flowers, directly shaping visual appeal and commercial value.
- Journal
- Horticulture Research