With the long-term on-orbit operation of the China Space Station, using nanosatellite swarms for cooperative observation of its external structures has become an important technical direction for enhancing in‑orbit monitoring capabilities. However, the space station itself has a non‑spherical complex geometry (e.g., protruding structures such as modules and docking ports) and may perform attitude maneuvers (e.g., sun‑pointing) during orbital flight, making it a dynamic obstacle with both intricate shape and rotational motion relative to the nanosatellites. Traditional artificial potential field obstacle avoidance methods mostly simplify obstacles as spheres or ellipsoids, which cannot accurately characterize the composite geometric features of the space station, and usually ignore the obstacle's own rotational motion. This leads to difficulties in constructing the repulsive potential field, limited maneuvering space, and, more critically, a lack of rigorous theoretical proof to guarantee closed-loop system stability and collision avoidance. Therefore, developing a nanosatellite formation control method that can handle rotating non‑spherical obstacles while providing strict stability guarantees is of significant theoretical importance and engineering value for ensuring safe fly-around and efficient cooperative observation in the vicinity of the space station.

Deep inside Armenia's Ararat-1 Cave, ancient stone tools are rewriting the survival playbook of Middle Paleolithic hunter-gatherers. By contrasting meticulously repaired, long-distance obsidian tools with quick-fix local chert, a new study reveals how early humans mastered both extensive travel and on-the-fly resourcefulness. Rather than just a simple shelter, the cave emerges as a prehistoric pit stop—a crucial rest and repair station along complex migration routes.

Candida auris is a rising global health threat due to multidrug resistance, emphasizing the urgent need for novel antifungal strategies. The C. auris glycosylphosphatidylinositol transamidase (GPI-T) complex is the key enzyme that mediates the attachment of GPI anchors to target proteins.

Researchers have identified a critical genetic pathway involving the protein FOXO1 that maintains the health of the epididymis, a vital component of the male reproductive system. The study reveals that the age-related decline of this pathway drives cellular senescence and infertility. Furthermore, experimental treatments using specialized stem cells demonstrated the ability to restore this pathway, offering a promising new strategy for preserving male reproductive longevity.

The gold standard for treating a heart attack—rapidly restoring blood flow—comes with a deadly catch. This sudden reoxygenation often triggers a secondary wave of tissue destruction known as ischemia/reperfusion injury. Now, a study published in Protein & Cell unveils a revolutionary strategy to neutralize this "reperfusion shock" using a recombinant protein called human MG53 (rhMG53).

Childhood adversity has been linked to many types of diseases; however, the underlying biological mechanisms remain inadequately explored, hindering the development of preventive programs and targeted interventions. The plasma proteome has become a promising tool for investigating the mechanisms underlying disease development in recent years. What are the plasma proteomic signatures of childhood adversity, and how do they contribute to the associations of childhood adversity with diseases?

 Researchers have uncovered the initial adaptive mechanisms of Bacillus velezensis C5 when exposed to polyethylene microplastics. Using comparative transcriptomics, the study revealed a robust, polymer‑specific transcriptional program distinct from general starvation or surface‑contact responses. Exposure to polyethylene triggered massive upregulation of genes involved in biofilm formation and sporulation, while genes associated with canonical degradation were not induced. The bacterium remained viable without growth, formed dense biofilms, and increased surface hydrophilicity but caused only subtle physicochemical changes to the plastic. This survival‑first strategy represents a critical initial phase that must be overcome to enable efficient biodegradation.

Researchers have developed a hierarchical catalyst (NiNP‑BCN@C) featuring nickel nanoparticles encapsulated within a nitrogen‑doped carbon shell on a hollow‑rod carbon substrate. The hollow architecture maximizes exposure of Ni nanoparticles, while the carbon shell suppresses the competing hydrogen evolution reaction and promotes CO₂ activation. The catalyst achieves a CO Faradaic efficiency exceeding 90 % in an H‑cell and >98 % at 300 mA·cm⁻² in a flow cell, with a turnover frequency of ~93,579 h⁻¹ and stable operation over 32 h. In situ FTIR confirmed enhanced *COOH and COO⁻ intermediates, highlighting superior CO₂ adsorption and activation.