AI incorporates researchers’ knowledge and experience expressed in natural language into experimental planning, reducing the number of searches needed to reach target performance to one-quarter or less.

Pancreatic cancer cells are remarkably good at doing one thing: growing. But new Texas A&M research suggests that two tiny molecules already present in the body may help slow them down.

Researchers at the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) and the College of Education and Human Development found that increasing levels of two microRNAs, known as miR-15a and miR-16, reduced protein synthesis and slowed the growth of pancreatic ductal adenocarcinoma (PDAC) cells.

UIC College of Dentistry researcher Christine Wu found another reason to add these tart treats to your grocery cart: oral health.

Domestication has given cultivated carnations striking colors, varied forms, and long vase life, but often at the cost of fragrance. 

A team at XPANCEO has developed a way to turn advanced materials into clean, stable inks, pointing toward sensors that can be drawn by hand and, in time, become the functional layers of a smart contact lens. 

A review published in Cyber-Physical Energy Systems examines how IoT and machine learning technologies can transform manufacturing energy management. By enabling real-time monitoring, prediction, and optimization, these approaches offer new pathways for energy-efficient and sustainable factories while addressing key challenges in industrial adoption.

Freeze–thaw stress reduces baker’s yeast viability, delays fermentation restart, and weakens frozen-dough bread quality. Here, three independent Saccharomyces cerevisiae lineages were evolved for 300 generations under repeated freeze–thaw selection. Evolved populations showed markedly improved survival, with the best lineage reaching ~96% post-thaw viability, while retaining baseline growth capacity. In frozen dough, evolved lineages improved loaf expansion and texture retention after freezing. Physiological assays showed faster post-thaw recovery, stronger fermentation-associated activity, lower intracellular reactive oxygen species accumulation, altered antioxidant capacity, and better preservation of cell-envelope morphology. Transcriptomic, metabolomic, and cross-omics analyses of ALE1 linked these phenotypes to coordinated remodeling of carbon recovery metabolism, nitrogen redistribution, sulfur/glutathione-associated redox pathways, and membrane-related metabolites. These results show that ALE improves frozen-dough yeast performance through coordinated physiological and multi-omics remodeling rather than a single stress-response pathway.

Inflammation is central to coronary artery disease, yet many anti-inflammatory strategies have failed to improve cardiovascular outcomes. A new Science Bulletin review explains why and proposes a “4R framework”—right target, right patient, right timing and right benefit–risk balance—to guide precision anti-inflammatory therapy.

Deltamethrin disrupts gut bacteria and brain clock signaling, impairing antibacterial immunity in Nile tilapia through the brain–thyroid–immune axis. Dietary sodium butyrate alleviates this immune damage.

A research team has discovered a new low-energy thermodynamic response in the frustrated quantum magnet SrCu₂(BO₃)₂ by combining high-pressure, low-temperature, and magnetic-field measurements. Using advanced calorimetry techniques, the team observed a robust T-linear specific heat region near the pressure-induced first-order transition between the plaquette-singlet and antiferromagnetic states. This finding reveals a previously unexplored regime of gapless excitations in a quantum magnetic insulator and offers new opportunities for studying emergent phenomena in strongly correlated systems.