Researchers at the University of Science and Technology of China have developed an ultra-thin spray cooling heat sink only 3.5 mm thick and experimentally demonstrated its performance on a silicon-based thermal test chip. The study was published in Thermo-X.

Irinotecan is widely used for advanced solid tumours, but neutropenia (NP) remains a major dose‑limiting toxicity. This review summarises the pathogenesis, risk factors, and management of irinotecan‑induced neutropenia (IIN). IIN is primarily driven by SN‑38‑mediated topoisomerase I inhibition and mitochondrial injury in haematopoietic stem cells. Risk factors include irinotecan dosage, UGT1A and transporter gene polymorphisms, patient characteristics, organ function, and concomitant chemotherapy. Management strategies include genotype‑guided dosing, G‑CSF, alkalinising agents, and microbiota modulation. Integrating pharmacogenetics and supportive care may improve treatment safety and continuity.

The discovery of NFATC2 as a regulator of cellular “mechanical memory” could deepen understanding of cell migration in cancer metastasis, wound healing and fibrosis, while informing future tissue-engineering approaches.

A research team at City University of Hong Kong (CityUHK) has developed a new optical corner detection imaging method, which uses azimuthal Hilbert transform metasurfaces and is designed to work as a universal framework. The study marks an important advance in high-speed, low-power optical information processing and has demonstrated potential for motion tracking applications.

Using MODIS observations from 2003 to 2024, researchers evaluated candidate regions and seasonal windows for marine cloud brightening (MCB) worldwide by examining how key cloud properties varied with aerosol optical depth (AOD). Among five representative ocean regions, the North Pacific during boreal autumn (SON) showed a favorable coordinated pattern: cloud fraction and cloud optical thickness were positively sensitive to AOD, whereas cloud droplet effective radius was negatively sensitive. The study provides an observational basis for further evaluation of MCB candidate regions and seasonal windows. The findings were published in Science China Earth Sciences.

A review published in UroPrecision synthesizes clinical evidence on high-intensity focused ultrasound for localized prostate cancer and highlights that intraoperative prostate compression is a promising technical refinement that enhances treatment precision and outcomes.