The new cholesterol guideline: What to know
Peer-Reviewed Publication
Updates every hour. Last Updated: 13-Jun-2026 13:15 ET (13-Jun-2026 17:15 GMT/UTC)
For the first time since 2018, a clinical guideline from the American College of Cardiology and the American Heart Association for screening and managing blood cholesterol levels has been updated and jointly published in the Journal of the American College of Cardiology and Circulation. The new guideline will be discussed March 28 at the American College of Cardiology’s 75th Annual Scientific Session in New Orleans.
The guideline’s release also ran a week before a paper titled “The ABCs of Cardiovascular Disease Prevention: Communicating What We Know in 2026” published in the American Journal of Preventive Cardiology.
Chinese researchers identified tumor-specific MHC-II (tsMHC-II) expression as a novel biomarker predicting response to neoadjuvant immunotherapy in gastric cancer. Single-cell profiling revealed higher MHC-II expression in tumor cells from treatment-sensitive patients. Validated in prospective trials, tsMHC-II-positive patients achieved 36.67% pathological complete response rate versus low rates in unselected populations. This simple immunohistochemistry-based biomarker outperforms current PD-L1 assessment and could guide personalized therapy for gastric cancer patients.
Dynamic switching between revival stem cells and conventional intestinal stem cells enables efficient tissue repair without exhausting the stem cell pool, report researchers from Institute of Science Tokyo. Using organoid and mouse disease models, the researchers uncovered how flexible stress-tolerant cell states contribute to intestinal repair—providing a better understanding of the biological mechanisms driving intestinal regeneration.
A new tool that not only identifies diet and nutrition misinformation online but also evaluates the content’s risk for potential harm has been developed by a team of UCL researchers.
Older adults who develop delirium during a hospital admission face a substantially higher risk of dementia in later years, even if they had no prior health conditions, according to a major new population study.
A review in the Chinese Medical Journal underscores healthy lifestyles as key to mitigating cardiometabolic risk. It emphasizes "Life's Essential 8," linking diet, physical activity, sleep, and other factors to significantly reduced risks of cardiovascular disease and type 2 diabetes. Despite proven benefits, widespread adoption faces challenges, necessitating innovative public health strategies and individual commitment.
A new overview of the best available evidence worldwide for smoking cessation has found that nicotine‑containing e‑cigarettes appear to be more effective for smoking cessation than other interventions..