About The Study: In this cohort study of more than 1,900 patients in randomized clinical trials (RCTs) for advanced epithelial ovarian cancer, Black and Asian patients were underrepresented compared with the general population estimates in the U.S., and Black patients had worse survival outcomes compared with white and Asian patients, despite having similar progression-free survival. Equitable enrollment in clinical trials ensures access to cutting-edge treatments and can lead to outcomes comparable to those of white counterparts. Sustained efforts to improve RCT diversity remain essential to long-term equity in cancer care and survival. 

When harmful bacteria that cause food poisoning, such as E. coli, invade through the digestive tract, gut cells usually fight back by pushing infected cells out of the body to stop the infection from spreading.

In a new study published today in Nature, scientists from Genentech, a member of the Roche Group, in collaboration with researchers from Oregon Health & Science University, discovered that a dangerous strain of E. coli — known for causing bloody diarrhea — can block gut this defense, allowing the bacteria to spread more easily.

Findings from a randomised and blinded clinical trial investigating repeated ketamine infusions for treating depression have revealed no extra benefit for ketamine when added onto standard care for people admitted to hospital for depression. The paper is published in the journal JAMA Psychiatry