Beyond wrinkles: Scientists discover a new rule that explains why growing shapes suddenly crumple
Peer-Reviewed Publication
Updates every hour. Last Updated: 29-Oct-2026 18:16 ET (29-Oct-2026 22:16 GMT/UTC)
Scientists have discovered a previously unknown law of geometry that explains why some growing surfaces, whether in nature or engineered materials, suddenly stop being able to stay smooth and instead form dimples and folds. Until now, researchers believed they understood the geometric rules behind these shape changes, but this study reveals a new kind of "geometric frustration" that arises even when all the known rules are satisfied. The finding could reshape how scientists understand the formation of leaves, flowers, tissues and other natural structures, while helping engineers design smarter materials that can deliberately change shape for applications in soft robotics, medicine and advanced manufacturing.
A joint research team from the National Institute for Environmental Studies (NIES), The University of Osaka, and Waseda University has developed a method to visualize the three-dimensional distribution of nanoplastics in the neonatal mouse brain without tissue sectioning. By combining tissue clearing with light‑sheet fluorescence microscopy, the researchers observed more extensive accumulation of 50 nm polystyrene nanoplastics than larger 500 nm particles in multiple organs—including the brain, intestine, and kidneys—following neonatal oral administration. Whole‑brain imaging revealed the widespread distribution of 50 nm particles, with relatively higher signals in the thalamus and brainstem. This study establishes a foundational three‑dimensional imaging platform for investigating nanoplastic biodistribution during early development. Of note, environmental exposure levels and health risks are not directly assessed in the study, which focuses on the development of a key methodological tool for research in the field. This research article is scheduled for publication on June 29, 2026 in the Journal of Hazardous Materials Advances (Elsevier).
A clinical trial led by researchers at CU Anschutz has found that oral semaglutide, a medication widely used for diabetes and weight loss, reduces heavy drinking in adults with Alcohol Use Disorder (AUD). The study, published today in The American Journal of Psychiatry, evaluated the oral formulation of semaglutide, which may be more acceptable for people with AUD than the injectable formulations previously tested for AUD.
A new report led by researchers at the Keck School of Medicine of USC provides evidence-informed recommendations to help the Department of Veterans Affairs (VA) better identify and address intimate partner violence (IPV) among veterans. Convened under a provision of the Deborah Sampson Act of 2020, a multidisciplinary expert panel reviewed research summaries drawn from more than 100 studies and issued guidance for clinicians and policymakers.
The panel recommends expanding screening for IPV across all points of care, paired with enhanced training and resources for healthcare staff to recognize and respond to risk. It also emphasizes a “no wrong door” approach, ensuring that disclosures—regardless of where they occur in the health system—lead to appropriate support and intervention.
Findings highlight that IPV among veterans is often underrecognized and extends beyond physical and sexual violence to include psychological abuse and stalking. The report also identifies veteran-specific risk factors, including post-traumatic stress disorder (PTSD), elevated suicide risk, substance use and deployment-related stressors. Given the intersection of these risks with higher rates of firearm access, the panel recommends integrating safety planning into screening efforts.
The authors also found strong support for the VA’s existing National IPV Assistance Program, noting that its trauma-informed, veteran-centered approach remains aligned with current evidence. The recommendations, published in Women’s Health Issues and shared with VA leadership, are intended to help prioritize strategies that are both practical and likely to have the greatest impact.
Archaic human parents had to look after helpless infants like modern day parents do, according to new research. Human babies are born less developed than those of other great apes, and so are unable to move as freely. A common result of this is deformational plagiocephaly, also called flat head syndrome. Professor Yousuke Kaifu at the University of Tokyo led a team which studied head shapes from scans of living infants, historical Japanese skeletal remains, fossilized specimens of Homo erectus and Homo floresiensis, and compared these to measurements of dry skulls from other great apes. Human head shapes across the ages, as well as the fossilized samples, exhibited a far wider range of deformation. The team sees this as evidence that archaic humans birthed helpless infants, with implications for childcare practices and potentially cooperative social behaviors dating back hundreds of thousands of years.
Changing patterns of heat and daylight in urban environments are creating growing inequalities, with climate-related shifts reshaping daily life and disproportionately affecting vulnerable communities.
Researchers from the University of East Anglia (UEA) have examined how elemental conditions such as rising temperatures and changing daylight experiences influence the way people live, move and interact within cities - using London and Delhi as examples.