Innovative card deck by Case Western Reserve professor empowers kids to tackle stress head-on
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Updates every hour. Last Updated: 5-Jun-2026 15:16 ET (5-Jun-2026 19:16 GMT/UTC)
A Case Western Reserve University professor has developed an innovative card deck designed to help children manage stress and build emotional resilience in today’s challenging world.
The secret to youthful appearance and repairing scars may lie in a microscopic skin structure humans share with pigs and grizzly bears — but, surprisingly, not monkeys. While it had been thought these ridge and valley-like skin microstructures — called rete ridges — form during fetal growth, researchers at Washington State University’s College of Veterinary Medicine found they actually develop shortly after birth and identified a key molecular signal that drives their development.
This work, led by Xiuchun “Cindy” Tian, professor of biotechnology in the Department of Animal Science, and her former and current graduate students Yue Su, Jiaxi Liu, and Ruifeng Zhao, was published in Stem Cells.
Leveraging human organoid-based mechanistic investigation, researchers reveal how an immunosuppressive drug, antithymocyte globulin (ATG), induces injury to blood vessels in the liver. According to the study, ATG first triggers rapid clotting through a complement activation system and later causes inflammation by activating the TGF-β pathway. This discovery explains why some patients experience severe liver-related side effects following organ transplantation and aid in developing safer immunosuppressive regimen.