New study offers strong evidence of elevated heart failure risk in adults with prediabetes, hypertension and subclinical heart injury or stress
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Updates every hour. Last Updated: 19-Jun-2026 00:15 ET (19-Jun-2026 04:15 GMT/UTC)
A University of Iowa-led research team has documented in humans that physical exercise sparks an increase in brain waves called ripples connecting areas in the brain linked to learning and memory. The researchers noted that a single exercise session spawns a spike in ripples and learning-memory connections. Results published in the journal Brain Communications.
A new study finds that the more a state’s budget relied on sales tax revenue, the more likely it was to shorten stay-at-home orders during the early stages of the COVID pandemic. The findings suggest that state public-health decisions may have been influenced by unexpected budgetary constraints imposed by public-health restrictions.
The NF-κB-inducing kinase (NIK), a molecule pivotal for immune system development and function, shows significant yet complex potential as a therapeutic target. The comprehensive review, published by Professor Shao-Cong Sun’s team, systematically details the expanding understanding of NIK. This article summarizes its canonical roles, its newly discovered functions independent of NF-κB, and its pathological contributions to autoimmunity, framing both the opportunities and challenges in targeting this critical immune regulator.
Rotator cuff tears often heal with stiff, dysfunctional scar tissue, limiting recovery. A new study reveals why tendon regeneration fails after injury. Using single-cell profiling of tens of thousands of cells from patient tendon samples, the study maps the first atlas of human tendon scarring and identifies pro-fibrotic stem cells, senescent tendon cells, scar-forming macrophages, and transitioning endothelial cells. Targeting key fibrotic signals reduced scarring in animal models, suggesting new therapeutic strategies.
Flexible electronics have been drawing significant attention for healthcare applications and show great promise for monitoring of blood circulation (e.g., postoperative monitoring of free flaps). However, existing methods for design and fabrication of interfaces with human skin still cannot meet the challenging clinical requirements of superior adhesion during monitoring and avoiding wound damage during peel-off. Now, writing in the journal National Science Review, a team of researchers from China and Singapore proposes a soft biosensor with universal responsive hydrogel interfaces for detecting blood circulation complications. They develop thermoresponsive and printable hydrogel inks to achieve rapidly high-precision patterning and wide-range adhesion regulation of interface layers. In clinical cases, the hydrogel biosensor can establish robust hydrogel/flap skin coupling for high-fidelity signal acquisition during monitoring, and ensure benign detachment to prevent tissue injury after monitoring. They achieve precise arterial perfusion monitoring based on the perfusion index (PI) via an 810 nm light source. Additionally, they propose a new metric, the balance index (BI), to monitor venous congestion. By analyzing BI, PI, and skin temperature, the biosensor enables accurate detection and differentiation of blood circulation complications.