This cohort study of older traditional Medicare beneficiaries who were diagnosed with common metastatic cancers found a mean of 40 to 62 health care contact days in the year after diagnosis. Health care contact days increased from 2008 to 2019, suggesting that treatment advancements and/or care inefficiencies may have imposed additional burdens on beneficiaries. The results of this study suggest that oncology teams should discuss expected contact days and related burdens when developing care goals and treatment plans with older adult patients.

The American Federation for Aging Research (AFAR) and Hevolution Foundation are pleased to announce the third cohort of theHevolution/AFAR New Investigator Awardees in Aging Biology and Geroscience Research. This grant program enables junior investigators with labs in the US and Canada, and with at least three years of independent research, to advance research projects in basic biology of aging, as well as geroscience projects that translate advances in basic research on aging biology from the laboratory to the clinic, paving the way for healthspan-expanding therapeutics and treatments. $6,750,000 will support eighteen investigators selected to receive this three-year award of $375,000 (total).

Globally, respiratory syncytial virus (RSV) infections are one of the most common causes of severe lung infections in babies and young children and is responsible for thousands of hospitalizations and deaths in infants every year. Why does RSV affect babies more severely? To better understand the cellular reasons behind this age-related difference, a team at Baylor College of Medicine compared infant and adult human nose organoids, also called mini-noses, regarding their susceptibility and response to infection.

McGill University researchers have identified a brain function that helps explain why childhood stress raises metabolic health risks for some women later in life.

A new study found that variations in the brain’s insulin receptor network affect how women respond to early-life adversity. This effect has a lesser impact in men, suggesting there is a sex-specific process at play.