Spatial map of bladder cancer reveals hidden tumor environments and new paths toward precision therapy
Peer-Reviewed Publication
Updates every hour. Last Updated: 18-Jun-2026 17:16 ET (18-Jun-2026 21:16 GMT/UTC)
Spatial profiling of muscle-invasive bladder cancer reveals how different tumor cell states are organized within individual tumors
Bladder tumors are not simply “luminal” (more differentiated) or “basal” (less differentiated) but often contain both cell states arranged in distinct spatial patterns
Luminal tumor cores and basal-like invasive regions respond differently to treatments
Findings provide a framework that may inform precision therapy strategies tailored to the spatial tumor cell landscape of bladder cancer
As telehealth, remote monitoring, and artificial intelligence-powered health tools become increasingly integrated into healthcare delivery, a new study published in JAMA Network Open introduces the first comprehensive national measure designed to assess whether communities are prepared to benefit from digital health services.