Toyoake, Japan — A research team at Fujita Health University led by Professor Tsuyoshi Miyakawa has uncovered a novel mechanism of cellular plasticity in which repeated neuronal stimulation can durably alter the identity of mature neurons. Using a neural stimulation pattern termed "Repetitive Optogenetic Stimulation (REPOPS)," the researchers found that granule cells of the hippocampal dentate gyrus undergo long-lasting changes in nuclear structure and gene expression, revealing a novel process which the team terms “nuclear reprogramming.”

Herbularyo gets players acquainted with both organic chemistry and traditional Filipino medicine in as little as five to ten minutes of gameplay. The scientifically-grounded traditional Filipino remedies found in the game are based on real research from the Philippine Institute of Traditional and Alternative Health Care (PITAHC).

 

Lead is a highly toxic and persistent heavy metal that poses serious risks to human health. The detection of lead ions in water is therefore essential not only for balancing economic and environmental priorities, improving public services, and ensuring agricultural safety, but also for preventing lead poisoning, promoting health equity, and safeguarding international trade in the context of global health. Conventional detection methods are often limited by expensive instrumentation and complex procedures, whereas surface-enhanced Raman scattering (SERS) has emerged as a promising alternative due to its high sensitivity and operational simplicity.

The issue of environmental pollution has got worse due to the quick expansion of manufacturing, industry, and human society. Among different pollutants, the emission impact of volatile organic compounds (VOCs) has been steadily expanding, posing a significant challenge to human health. Gas sensors are devices that convert gas concentration from chemical to electrical signals and play a central role in real-time gas detection system.

A research group is developing a portable rapid diagnostic system for Ebola virus disease caused by Bundibugyo virus. The project has been selected for funding by the Global Health Innovative Technology Fund.

 The study investigated serum concentrations of multiple elements and copper isotopic fractionation in healthy, anemic, and overweight or obese children, to give metallome profiles and evaluate the feasibility of these elements and δ⁶⁵Cu as a potential indicator with metallome comprehensively for early subclinical status. This study addresses two of the most prevalent and impactful pediatric health concerns globally, anemia and childhood overweight/obesity, through an innovative multi-elemental and isotopic lens.

Human activities are fundamentally altering the chemical makeup of local coral reefs, according to a new study. The research team discovered that 25 contaminants from agricultural, industrial, and pharmaceutical sources accumulated in the soft tissues of coral around Maui, Hawai‘i. Additionally, in areas impacted by human activities, the energy and nutrient availability within the coral’s tissue decreases, making them significantly less resilient to environmental stressors such as warmer or acidic waters.

Ports connect cities, economies, and supply chains, but they also create environments where marine ecosystems interact intensely with shipping, wastewater, and coastal development. A new global study has revealed that these pressures leave measurable signatures in the microscopic communities living in port waters.