A research paper by scientists at Capital Medical University validates the necessity of integrating cognitive–motor strategies for the motor rehabilitation of PD and identifies novel neural markers for assessing treatment efficacy.

The new research paper, published on Jun. 19, 2025 in the journal Cyborg and Bionic Systems, presented neuroplasticity driven by attentional network activation and the dynamic reallocation of attentional resources are the core mechanisms by which short-term MIRT facilitates compensatory motor function and the necessity of developing intervention strategies that integrate cognitive–motor dual regulation.

Growth charts for children with rare genetic disorders - giving healthcare professionals and families clearer guidance on how a child is developing - have been created by an international team, led by the University of Bristol.

Researchers have improved the ability of wearable health devices to accurately detect when a patient is coughing, making it easier to monitor chronic health conditions and predict health risks such as asthma attacks. The advance is significant because cough-detection technologies have historically struggled to distinguish the sound of coughing from the sound of speech and nonverbal human noises.

Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disease, and approximately 90% of cases are caused by progerin. Progerin is toxic and causes diverse abnormalities. More and more studies show that progerin is also detected in physiological aging and chronic kidney disease (CKD). Thus, targeting progerin clearance shows powerful potential for the treatment of HGPS, CKD and aging-related diseases. Now, Zhang group from Peking University and Kunming University of Science and Technology, reports that activating lysosome biogenesis can promote progerin clearance and alleviate cellular senescence in HGPS. They identify lysosome defects as a prevalent feature in HGPS, which impairs progerin clearance, and reveal that activating lysosome biogenesis can counteract lysosome defects and accelerate progerin clearance and mitigate DNA damage, cell cycle arrest, low proliferation ability and senescence-associated secretory phenotype (SASP) in HGPS cells. The findings highlight the vital role of lysosomes in progerin clearance, and uncover the potential of targeting lysosome biogenesis in anti-senescence.

In an article published in the journal Kriminologie, a team of researchers from the universities of Castelló and Alicante suggest that the effects of underwater noise pollution should be included in international criminal and administrative law.

Anthropogenic noise can be not only a serious public health problem, but also a significant stressor for marine and terrestrial life. Scientific evidence has shown that there is a cause-and-effect relationship between underwater noise pollution and the development of some species, and although it has been identified by the World Health Organisation as one of the world's most important pollutants, comprehensive strategies to address its impact on the marine environment have only been developed in the last decade.

After analysing international legislation on the subject, the team believes that this type of pollution "needs to be addressed in a single but integrated approach" because even if the activities are authorised, their effects can be difficult to reverse. In their view, "the law must deal with the protection of the environment in a comprehensive manner" and develop a model of protection that includes administrative sanctions, but also criminal sanctions in very serious cases.