Rodney Scott, MBChB, MRCP, DipStat, PhD, Division Chief of Neurology, Nemours Children’s Health, Delaware Valley, has received a prestigious National Institutes of Health (NIH) Director’s Transformative Research Award. Dr. Scott will use the $2.6 million, five-year grant to investigate malfunctions in the brain’s hippocampal region, aiming to identify patterns that could lead to shared therapies for patients with autism, epilepsy, and Alzheimer’s disease.

Researchers at UC San Diego School of Medicine have discovered a previously unrecognized mechanism by which skin bacteria delay wound healing.

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications from catalysis to medicine to manufacturing.

Researchers have identified a novel brain circuit that helps animals swiftly respond to perceived threats— and dial down that response when they learn there’s no real danger. In people with anxiety disorders, this circuit may be broken.

About The Study: In this study, major adverse cardiovascular event risk varied significantly by medication class, with most protection achieved with sustained treatment with glucagon-like peptide-1 receptor agonists (GLP-1RAs) followed by sodium-glucose cotransporter-2 inhibitors (SGLT2is), sulfonylureas, and dipeptidyl peptidase-4 inhibitors. The magnitude of benefit of GLP-1RAs over SGLT2is depended on baseline age, atherosclerotic cardiovascular disease, heart failure, and kidney impairment. These results, along with consideration of cost, availability, and collateral clinical benefits, may inform treatment decisions for adults with type 2 diabetes.