About The Study: In this survey study, direct patient or caregiver prior authorization (PA) engagement was associated with adverse outcomes, including delays, not receiving care as prescribed, and negative perception of PA. This is consistent with prior research describing patient-reported delays and suboptimal care. This study may be used to shape future research and intervention development to help patients, caregivers, clinicians, and advocates navigate PA-related administrative burden.

Researchers have found that a combination of enfortumab vedotin and pembrolizumab helps patients with muscle-invasive bladder cancer live longer while reducing the risk that their cancer will return after surgery, according to an international phase 3 clinical trial published in The New England Journal of Medicine (DOI: 10.1056/NEJMoa2601486).

New research has shown that RNA-based testing can improve the detection and interpretation of clinically actionable genomic alterations leading to MET exon 14 skipping in lung cancer patients—important biomarkers that may be missed by DNA-only approaches. The findings from the study appearing in The Journal of Molecular Diagnostics, published by Elsevier, are poised to lead to improved diagnostic accuracy and help determine patients’ eligibility for MET-targeted therapies.

Metabolic dysfunction-associated fatty liver disease (MAFLD) represents a predominant cause of chronic liver disease, underscoring the demand for accessible, non-invasive diagnostic tools. Tongue diagnosis in Traditional Chinese Medicine provides a distinctive perspective on systemic health, though it remains largely subjective. This study aimed to develop an interpretable multimodal deep learning model for MAFLD screening by integrating quantitative tongue image features with routine clinical data.

Based on UK COVID Symptom Study Biobank data collected in the early years of the pandemic, experts from King’s College London and Flinders University in Australia have carried out one of the first large-scale longitudinal studies to assess the extent of residual or continuing sleep and related mental health problems, including people with 'long COVID'

Earlier toilet training and new recycling technologies are among expert-backed solutions to reduce the environmental impact of disposable nappies and other hygiene products, described in a new study led by UCL researchers.