About The Study: This statewide cohort study found that childhood mortality is significantly higher among children bereaved by parental drug overdose, homicide, and suicide compared with the general child population. Parental homicide was associated with the highest risk of mortality in children and highlights the need for research into potential explanations, such as the impact on family restructuring and mental health.

About The Study: In this multicenter randomized clinical trial among older adults with family history of dementia and/or self-reported subjective cognitive decline, exercise, intensive pharmacological reduction of cardiovascular risk factors, or both did not result in statistically significant differences in improvements in cognitive function over 24 months.

About The Study: In England’s health care system, multiple sclerosis prevalence more than doubled while survival rates increased over 30 years. Substantial gradients in tobacco use, abnormal weight, and socioeconomic deprivation persisted and were associated with mortality.

About The Study: The results this cohort study suggest that children ages 7 to 17 with metabolically healthy obesity at treatment initiation have an increased associated long-term risk of type 2 diabetes, hypertension, and dyslipidemia compared with their peers in the general population. Reduction in BMI z score in pediatric obesity treatment was associated with reduced cardiometabolic risk in children with metabolically healthy and unhealthy obesity to the same extent. Therefore, treatment should also be recommended for children with obesity who appear metabolically healthy. 

About The Study: Using Fitbit data in a longitudinal cohort of 3,393 young adolescents, 6 sleep health dimensions were identified: irregularity, timing, duration, social jetlag, weekend oversleep, and continuity. Greater irregularity was associated with higher concurrent transdiagnostic mental health symptoms, whereas shorter duration was associated with higher symptoms at 1-year follow-up. These findings demonstrate the multidimensional nature of adolescent sleep health and can help guide selection of sleep health domains and representative measures to enhance reproducibility and suggest potential intervention targets.

About The Study: This systematic scoping review study of prescription drug promotion by influencers found that such promotion carried risks of inaccurate or misleading advice, often amplified through personal and emotionally resonant narratives in an environment with limited oversight and enforcement. Despite the small and fragmented evidence base, these findings highlight the urgent need for updated regulatory guidance, standardized and enforceable disclosure requirements, stronger platform accountability, and targeted digital literacy initiatives. Policymakers and researchers should act proactively to safeguard public health.

Multiple sclerosis (MS) has more than doubled in recorded prevalence in England from 2000 to 2020, increasing by 6% per year, largely due to improved diagnosis and longer life expectancy, finds a new study by University College London (UCL) and Imperial College London researchers.

Dr. Jeffrey Keller of Pennington Biomedical Research Center explores whether exercise and intensive cardiovascular risk reduction could improve cognitive function in older adults at risk for Alzheimer’s disease In a recent study, researchers found that exercise and aggressive cardiovascular risk reduction successfully improved heart health, but these efforts did not produce measurable cognitive benefits over two years in older adults at risk for Alzheimer's disease. In “Effects of Exercise and Intensive Vascular Risk Reduction on Cognitive Function in Older Adults - A Randomized Clinical Trial,” published in JAMA Neurology, researchers, including Dr. Jeffrey Keller of Pennington Biomedical Research Center, shared the results of the Risk Reduction for Alzheimer’s Disease (rrAD) study. They found that interventions that successfully improved cardiovascular health did not translate into measurable cognitive benefits over two years, highlighting a critical gap between vascular risk reduction and brain health.