Spanning 350 square metres, the new Centre brings together state-of-the art facilities within an integrated multidisciplinary framework to enable clinical research and implementation of gerodiagnostics and gerotherapeutics, enhancing and optimising healthspan throughout the adult lifespan and setting new benchmarks for healthy longevity research and innovation.

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint precise areas of the body can reduce the medicine dosage and avoid potentially harmful “off target” effects. Researchers at the UW took a significant step toward that goal by designing proteins with autonomous decision-making capabilities. By adding smart tail structures to therapeutic proteins, the team demonstrated that the proteins could be “programmed” to act based on the presence of specific environmental cues. 

In September, 2019, Department of Health and Social Care of UK released UK Physical Activity Guidelines nationwide, which is broken down by age group: under 1, 1-4, 5-18, 19-64  and older adults aged >65 years, respectively. To date, the impact of adherence to physical activity guidelines by older adults on cardiorespiratory fitness and skeletal muscle mass, which are both key parameters of intrinsic capacity, is poorly understood. Therefore, the team from Centre of Metabolism, Ageing & Physiology (COMAP) from University of Nottingham recruited 14 older adults (age: 66-80 years) completed a 4-week intervention in which they adhered to UK Physical Activity Guidelines via a combination of supervised and home-based exercise, aiming to assess the impact upon parameters related to intrinsic capacity in older adults.

Skeletal muscle regeneration research is hindered by the "photodamage-imaging quality" trade-off in three-photon microscopy (3PM). A team from Zhejiang University developed the Multi-Scale Attention Denoising Network (MSAD-Net) to address this: combining MSAD-Net with 3PM reduces excitation power to 1.0–1.5 mW (1/4–1/2 of conventional levels) and scanning time to 2–3 μs/pixel (1/6–1/4 of standard), while maintaining 0.9932 SSIM and real-time denoising (80ms/frame). The system enables five-channel deep in vivo imaging of mouse muscle, uncovering key roles of macrophages and blood vessels in muscle stem cell-mediated repair.

Researchers in Japan have conducted the first nationwide survey of patient and public involvement and engagement (PPIE) in allergy research, revealing a striking gap between patient advocacy groups (PAGs) and researchers. While PAGs show strong commitment to collaboration, researcher awareness and implementation of PPIE remain limited. The study was recently published in Allergy, the official journal of the European Academy of Allergy and Clinical Immunology (EAACI), and its findings were also presented at the Science Summit at the 80th United Nations General Assembly (UNGA) in September 2025.

Proanthocyanidins, also known as condensed tannins, are a class of flavonoid polymers with multiple health benefits such as antioxidant, anti-tumor, and eye-protective effects. Now, researchers have discovered that the TaMYB10 gene controls the presence or absence of condensed tannins in wheat grains. Their findings reveal that TaMYB10 directly activates the expression of core flavonoid pathway genes CHS and DFR, initiating condensed tannin synthesis.