At two years of follow-up, patients with a poorly functioning tricuspid valve in the heart who received optimal medical therapy plus a minimally invasive procedure using a clip to repair the valve were significantly less likely to die, have a heart attack or stroke and 40% less likely to be hospitalized for heart failure compared with similar patients who were randomly assigned to optimal medical therapy alone. The study was presented at the American College of Cardiology’s Annual Scientific Session (ACC.26).

In the first head-to-head comparison of two devices intended to protect against stroke in patients undergoing transcatheter aortic valve replacement (TAVR), the investigational Emboliner device performed comparably to the Sentinel device, which is approved by the U.S. Food and Drug Administration. The research was presented at the American College of Cardiology’s Annual Scientific Session (ACC.26).

In patients with a poorly functioning bioprosthetic mitral valve in the heart, a minimally invasive procedure to insert a new valve was associated with a lower rate of death or disabling stroke within one year, compared with patients who underwent standard repeat mitral valve replacement surgery, according to a study presented at the American College of Cardiology’s Annual Scientific Session (ACC.26).

Older patients with coronary artery disease scheduled for transcatheter aortic valve replacement (TAVR) had comparable outcomes regardless of whether they underwent percutaneous coronary intervention (PCI) before TAVR, according to findings from the PRO-TAVI study presented at the American College of Cardiology’s Annual Scientific Session (ACC.26).

About The Study: Extended low-intensity anticoagulation with apixaban was associated with a reduction in symptomatic superficial vein thrombosis (SuVT) in patients with provoked venous thromboembolism with enduring risk factors for recurrence. Further randomized clinical trials specifically focused on SuVT are needed to ascertain optimal antithrombotic strategies in broader populations at risk of SuVT.

About The Study: After multivariable adjustment, serum neurofilament light chain (sNfL) levels were associated with a broad range of adverse cardiovascular events and mortality in patients with atrial fibrillation (AF). Serum NfL may serve as a biomarker of cardiovascular risk in patients with AF.