Growth impairment is a common late effect of childhood stem cell transplantation. A Japan-wide study found that growth hormone therapy improves adult height, but prior radiation therapy and transplant-related complications negatively affect how much children benefit.

Medication-related osteonecrosis of the jaw (MRONJ) can be difficult to treat once it develops, making prevention especially important. In a retrospective study, a Hiroshima University researcher found that quantitative measurements extracted from CT images taken before treatment, when analyzed with machine learning, could distinguish patients who later developed the condition from those who did not—an early step toward predicting MRONJ risk before bone resorption inhibitor therapy begins.

A new pulse oximeter device can now read accurate blood oxygen saturation levels regardless of skin tone, age, and other factors that often introduce errors in many devices used in clinics today. 

Optimal containment measures exhibit a clear threshold depending on the severity of the disease

More than 60% of adults in Estonia have at least one chronic condition, and 42% are living with at least two chronic conditions. The most comprehensive population-based study conducted to date by researchers of the University of Tartu shows that people with multiple chronic conditions make significantly greater use of healthcare services and face a markedly higher risk of premature death or treatment-related complications than those without chronic conditions. The study is based on the new EST-Health-30 research dataset, which includes health data from nearly one third of Estonia’s population.

Portal hypertension is a serious complication of chronic liver disease that can lead to life-threatening conditions such as internal bleeding and liver failure. A new study examines how advances in imaging, blood-based biomarkers, predictive models, and artificial intelligence are reshaping the non-invasive diagnosis of the condition. By bringing together the latest evidence, the review highlights how these approaches could support earlier detection, improve disease monitoring, and reduce the need for invasive procedures.