A multinational research team led by Shanghai University has published a comprehensive review detailing the biological characteristics of extracellular vesicles (EVs), their interaction mechanisms with the cardiovascular system, and cutting-edge bioengineering strategies to enhance EV functionality. The review highlights that bioengineered EVs, with optimized targeting and cargo delivery capabilities, show great clinical potential in protecting the myocardium, regulating vascular homeostasis and promoting cardiac regeneration, opening a new era for precision therapy of cardiovascular diseases such as myocardial infarction and heart failure.

A groundbreaking study unveils how coronaviruses, including SARS-CoV-2, hijack a host protein called HGS to create large, specialized "vesicles" that act as efficient virus assembly factories during late infection. Using advanced imaging, the team visually confirmed viruses being built inside these structures. Disabling HGS drastically reduced virus production, identifying it as a promising new target for broad-spectrum antiviral drugs.

Prostate cancer screening compares favourably to screening for breast cancer in identifying significant cancers, reducing mortality and avoiding unnecessary harms, says new research.

New research co-led by Liu-Qin Yang, a professor of psychology at Portland State University (PSU), suggests that the true damage of a toxic boss goes far deeper than a bad mood — it fundamentally alters how employees perceive their own humanity. Published in the Journal of Occupational Health Psychology, the study identifies “organizational dehumanization” as the primary mechanism that strips employees of their agency, leading to severe burnout and a collapse in workplace collaboration.