Mayo Clinic researchers have developed a new method to identify which proteins are most likely to trigger an immune response — a discovery that could help improve transplant care, regenerative medicine and other areas where the immune system plays a critical role. The results, published in Biomaterials, challenge a common assumption in the field that all proteins are equally likely to provoke immune reactions.

About The Study: Among patients with commercial insurance, manufacturer-sponsored coupon use declined substantially between 2017 and 2024, whereas per-claim coupon amounts increased. These patterns may reflect several mechanisms. Manufacturers may be concentrating coupon programs on fewer products or for fewer patients while offering larger incentives in response to formulary pressures or expanded copay accumulator programs. Greater coupon amounts may also reflect higher underlying patient cost-sharing requirements.

About The Study: In this cohort study, a $35 monthly insulin out-of-pocket cap was found to be associated with significantly lower insulin out-of-pocket spending, increased access to insulin, and decreased blood glucose levels among Medicare beneficiaries with type 2 diabetes. These findings suggest federal cost-sharing policies could improve access and adherence to essential medications in diabetes and other chronic diseases. 

University of Michigan researchers have identified a new target that can suppress tumor growth.

Their findings may lead to new treatment methods for gastroenteropancreatic neuroendocrine tumors.

Analysis of hundreds of environmental exposures and health outcomes quantifies influence of nongenetic factors