Clinical trial in Africa finds single-dose malaria treatment combining four existing drugs as effective as more onerous multi-day, multi-dose regimen
Reports and Proceedings
Updates every hour. Last Updated: 14-Jan-2026 01:11 ET (14-Jan-2026 06:11 GMT/UTC)
TORONTO (November 12, 2025) —Hundreds of malaria patients participating in a clinical trial in Gabon in West Africa were cured via a single dose of a treatment that utilizes four widely available malaria drugs, according to a new study presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).
Rainfall and flooding frequently disrupt the lives of urban residents worldwide, posing significant public health risks. Mumbai, India - renowned for the ferocity of its monsoon season - stands as a stark example of the human toll that extreme urban flooding can exact. But despite the growing recognition and urgency of these hazards, the health impacts of rainfall remain poorly understood, and those of sea level rise are entirely unquantified. A recent study led by Princeton University and the University of Chicago takes a closer look at the intersection between climate change, hazards, and public health in Mumbai, finding that deaths caused by rainfall and rising sea levels are almost ten times higher than the official statistics suggest.
A bold new research collaboration, backed by a prestigious $3 million Terry Fox New Frontiers Program Project Grant, is setting out to bridge scientific fields and unlock the answer to this all-important question central to patient care. Led by Dr. Michele Ardolino, the team of investigators will seek to uncover the hidden mechanisms of how the body’s immune system, nervous system, and gut microbiome interact in cancer. Their cross-disciplinary work and innovative approach has the potential to fundamentally reshape cancer treatment.