A new molecular switch, created through protein design, may be a potential way to control when drugs are active or inactive in the body. Researchers hope this approach is a starting point for further developments to reduce side effects from cancer drugs or antibody therapies. This type of designed molecular switch has already been shown to increase the speed of a COVID test. The scientists have also created a switchable version of interleukin-2 in a effort to manage the side effects of this potentially powerful cancer drug. 

A cutting-edge bronchoscope that is guided with the help of a robot can reach very small tumours growing in hard-to-reach parts of the lung, according to results of a gold-standard randomised-controlled trial that will be presented at the European Respiratory Society Congress in Amsterdam, the Netherlands. The robot-assisted bronchoscope also uses a specialised CT scanner to find tumours buried in the lungs, enabling doctors to take a biopsy and confirm whether they are cancerous. Being able to find and test these very early cancers gives patients the highest chances of being cured.

From influenza and COVID-19 to HIV, viruses continue to pose a serious danger to global health. But just as pressing are threats from other disease-causing microorganisms such as bacteria—especially the deadly strains that are becoming resistant to antibiotic medicines. And increasingly, scientists are discovering how viruses and bacteria are closely interconnected, influencing health and disease in ways that we’re only beginning to understand. To reflect these realities, the Gladstone Institute of Virology has taken on a new name: the Gladstone Infectious Disease Institute. 

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that Andreea Creanga, MD, PhD, a distinguished and internationally recognized leader in maternal and perinatal health, has been appointed the new Chair of the Department of Epidemiology and Public Health. She will also be installed as the Simon and Bessie Grollman Distinguished Professor. Her appointment is effective December 2025.