PKU scientists develop first-in-class drug candidate for cholestatic itch
Peer-Reviewed Publication
Updates every hour. Last Updated: 11-Jun-2026 13:15 ET (11-Jun-2026 17:15 GMT/UTC)
Polyendocrine Metabolic Syndrome (PMOS), formerly PCOS, is the most common hormonal and metabolic disorder in women of reproductive age, affecting up to 13% and contributing to nearly 40% of infertility cases. FAU researchers reviewed more than 2,200 studies and identified 29 focusing on non-pharmacological care in midlife and reproductive aging. Findings of the analysis show lifestyle interventions – especially diet and exercise –are most consistently supported, while evidence for complementary therapies is limited and chronic pain and mental health remain largely understudied.
The intravenous infusion of mesenchymal stem cells from family donors is safe and improves symptoms such as pruritus (itching), sleep disturbances, and fatigue associated with Recessive Dystrophic Epidermolysis Bullosa (RDEB), popularly known as "butterfly skin". This is one of the primary conclusions of a clinical trial conducted by researchers from the Universidad Carlos III de Madrid (UC3M), the Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT) of the Ministry of Science, Innovation and Universities, the Fundación Jiménez Díaz Health Research Institute (IIS-FJD), the CIBER Rare Diseases (CIBERER), and the La Paz University Hospital in Madrid.
Gathering dust from buildings may hold promise as a more efficient way to track viral outbreaks in indoor settings, according to a new study.
Most prostate cancers rely on male sex hormones, known as androgens, to grow. As a result, standard treatment focuses on lowering androgen levels or blocking their activity, but many tumors eventually become resistant and the disease returns.
In a study published in EMBO Molecular Medicine, an international research team led by Prof. Yosef Yarden of the Weizmann Institute of Science identifies a major cause of this resistance. A common genetic alteration found in roughly half of prostate cancers – the fusion of two genes – enables tumors to bypass their dependence on male hormones and instead rely on another steroid hormone: cortisol.