Proteins that create ice inspire ‘cool’ applications
Peer-Reviewed Publication
Updates every hour. Last Updated: 14-Jun-2026 18:16 ET (14-Jun-2026 22:16 GMT/UTC)
Ice-nucleating proteins naturally bind only to organic surfaces, so understanding whether they can bind to human-made materials can help with applications like deicing, creating artificial snow, cryo-medicine, and more. In Biointerphases, researchers found that the proteins connect to a surface in a layer of single molecules with their ice formation side facing out, allowing ice to grow atop the surface, and that they do not seem to care what type of material they are binding to; for both artificial and natural surfaces, the INPs bind in remarkably similar ways.
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have discovered that many gut bacteria use a flexible survival strategy to withstand disruptions such as antibiotics and diet changes. Published in the May 19 online issue of Cell Host & Microbe (DOI: 10.1016/j.chom.2026.04.019), the study shows microbes can switch between functional states, rather than relying solely on genetic mutations, to try to survive shifting conditions. The findings shed light on a previously hidden layer of microbiome biology and may help explain why probiotics and fecal microbiota transplantation (FMT) produce inconsistent benefits across individuals.
A large, multi-center study led by Ann & Robert H. Lurie Children’s Hospital of Chicago derived “achievable benchmarks of care” (ABCs) using electronic health record data, which allows pediatric emergency departments across the country to set high yet realistic performance goals. The new benchmarks are based on high achievers – a shift away from relying on peer averages in performance metrics. The study is published in JAMA Network Open.
A research paper by scientists from Nanjing Medical University developed a biomimetic nanoparticle (NP) system composed of macrophage-membrane-coated Prussian blue@KGN (KGN@PB@CM) loaded into a thermosensitive Pluronic@F127/hyaluronic acid (HA-F127) hydrogel for synergistic tendon healing.
The new research paper, published on Apr. 23 in the journal Cyborg and Bionic Systems, developed a biomimetic nanoparticle system that simultaneously tackles clinical challenges, accelerating tendon repair through a “dual‑modulation” approach.
Understanding the packing and folding of DNA in sperm cells is a fundamental question in modern biology, related to infertility and to genetic and developmental defects. UC Davis researchers have now unveiled an important new piece of this puzzle. They have identified a protein, called DAXX, that guides how sperm DNA is organized, silences numerous genes and keeps some switched on. The work was published recently in Genes & Development.