A recent review outlines major advances in hydrogel-based strategies for musculoskeletal therapy. Through refined material design and strengthened mechanical performance, hydrogels can mimic key extracellular matrix features while enabling localized and controlled delivery of drugs, cells, and other bioactive cues. They can also be engineered into clinically relevant formats, including injectable systems, scaffolds, patches, and adhesive sealants, supporting applications across bone and cartilage repair, osteoarthritis management, disc regeneration, tendon healing, and dural repair.
