Researchers from Donghua University and Yanshan University have developed an enhanced neural network called EF-YOLO, which significantly improves the automated detection of colorectal polyps—a key precursor to colorectal cancer. By integrating advanced modules such as transformer, deformable convolution, coordinate attention, and a newly designed multi-scale aggregation mechanism, the model achieves a mean average precision (mAP) of 96.60% on standard medical datasets. This represents a major step forward in reducing missed detections during colonoscopy and supporting early clinical intervention.

Recently, a research team led by Professors Dahong Zhang and Qi Zhang from the Urology Department and the Institute of Urology at Zhejiang Provincial People's Hospital and the Translational Medicine Center discovered that a bladder tumor-targeting polyarginine peptide, R11, can directly bind to actin, destabilize the G-actin tetramer, and trigger the cascade breakdown of the actin–plectin–vimentin/ITGβ4 axis (referred to as the “cytoskeletal domino effect”).

Researchers from Donghua University, in collaboration with ANTA Sports Products Ltd., have developed a one-step ultraviolet (UV) irradiation technology to significantly improve the thermal stability and hydrophilicity of medium molecular weight polyethylene (PE) fibers. By integrating crosslinking and grafting modifications using a cost-effective photoinitiator system and acrylic acid (AA) as a grafting monomer, the modified fibers exhibit excellent morphological integrity and mechanical performance at elevated temperatures (130–150 °C), while the water contact angle dramatically decreases from 105.0° (hydrophobic) to 48.4° (hydrophilic). This innovation offers a practical and scalable solution for expanding the application of PE fibers in high-temperature and dyeable textile production.

Skin flaps are essential in reconstructive surgery, but their success can be threatened when blood flow fails to reach the farthest tissue. 

Recently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research Fellow at Zhejiang Provincial People’s Hospital, published a review entitled “Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer”. Aligned with the paradigm shift toward precision medicine and individualized management in prostate cancer, this review systematically summarizes the adaptive changes in intratumoral androgen metabolism and androgen receptor (AR) signaling during disease progression from hormone-sensitive prostate cancer (HSPC) to castration-resistant prostate cancer (CRPC) and the highly aggressive subtypes (DNPC and NEPC) emerging during castration resistance, along with research advances in how these mechanisms contribute to therapy resistance. Furthermore, the review critically analyzes current challenges in studying prostate cancer resistance, and outlines future directions toward high-throughput, refined, and personalized strategies, emphasizing the integration of multi-omics technologies and novel in vitro and in vivo models to advance mechanistic insights into drug resistance, thereby establishing a scientific foundation for optimizing individualized therapeutic approaches.