Collagen, the body’s most abundant protein, has long been viewed as a predictable structural component of tissues. However, a new study led by Rice University’s Jeffrey Hartgerink and Tracy Yu, in collaboration with Mark Kreutzberger and Edward Egelman at the University of Virginia (UVA), challenges that notion, revealing an unexpected confirmation in collagen structure that could reshape biomedical research.

Recently, Insilico Medicine (“Insilico”) announces that the team, with the support of its generative chemistry engine, has developed a novel and highly selective FGFR2/3 dual inhibitor, which maintains efficacy against resistance mutations, shows potency in gastric cancer animal model, and demonstrates a more favorable safety profile compared to existing FGFR inhibitors. The findings have been published in the Journal of Medicinal Chemistry (JMC, IF=7.2)

A research team led by Professor Hajime Monzen and Dr. Hiroyuki Kosaka from the Department of Medical Physics at Kindai University has developed the world's first non-contact system for monitoring respiratory motion during X-ray and CT imaging procedures. This breakthrough technology, developed in collaboration with SMK Corporation, uses millimeter-wave sensors to precisely track patient breathing patterns without physical contact, offering a significant advancement in medical imaging accuracy.

An international collaboration led by Nagoya University in Japan sheds new light on the relationship between quantum theory and thermodynamics. The research group demonstrated that while the laws of quantum theory alone do not inherently prevent violations of the second law of thermodynamics, any quantum process can be implemented without actually violating the law. This surprising result suggests a peaceful coexistence between quantum theory and thermodynamics, despite their logical independence. This discovery could have profound implications for understanding the thermodynamic limits of quantum technologies, such as quantum computing and nanoscale engines. 

In an article featured in Science China Earth Sciences, researchers from Tianjin University elucidate the coupling relationship between soil fungi and reactive minerals in ecosystems by utilizing global fungal carbon stocks, mineral-associated carbon stocks, and high-resolution nanoscale secondary ion mass spectrometry. They also reveal the mechanisms of fungal-nanoparticle interactions belowground. These findings provide new insights into the critical role of microorganisms in soil carbon stability and storage.