A new metal–organic framework (MOF), APF-80, enables the crystalline sponge method to capture and analyze nucleophilic compounds. Alkaloids, a diverse group of biologically active compounds, usually damage MOF crystals and resist study. By incorporating multiple structural motifs, these guests are encapsulated inside APF-80, which allows high-quality crystallographic data collection. This development opens new possibilities for structural analysis, advancing drug development and biochemistry.

Arsenic leaking from abandoned gold mines can harm forest ecosystems by entering soils and affecting soil organisms. In a recent study, researchers tested forest soils with different chemical properties to see how they influence arsenic mobility and toxicity in springtails. Results showed juveniles were more sensitive to mobile arsenic, while adults responded to total arsenic. These findings highlight the importance of soil chemistry and life stage in arsenic risk assessment.

A study of clam shells suggests Atlantic Ocean currents may be approaching a “tipping point”.

Researchers at Harvard and Northwestern have developed a machine learning method that can design intrinsically disordered proteins with custom properties, addressing nearly 30% of all human proteins that are currently out of reach of AI tools like AlphaFold. The new approach uses automatic differentiation, traditionally a deep learning tool, to optimize protein sequences for desired properties.

Researchers from the Institute of Physics at Johannes Gutenberg University Mainz have succeeded in creating three-dimensional skyrmions, so-called hybrid skyrmion tubes, in synthetic antiferromagnets and have demonstrated for the first time that these skyrmion tubes move differently than two-dimensional skyrmions.

Three researchers at the University of Tennessee, Knoxville, have received National Science Foundation CAREER awards for their work developing molecules that facilitate pharmaceutical drug design and evaluation, designing phishing detectors and developing new materials for quantum technology.

Researchers from The University of Osaka have developed a polymeric adhesion system by introducing reversible bonds at the adhesion interface based on the formation and dissociation of host–guest complexes. The adhesive can be decomposed on demand using temperature or chemicals and reused multiple times. Visualization of the interface using neutrons revealed the mechanism underlying repeatable sticking and peeling. This technology can be used for sustainable material applications.