As the world’s population ages at an unprecedented rate, the field of longevity research is surging to the forefront of science and investment, highlighted by the rapid growth of events like the Aging Research and Drug Discovery (ARDD) conference. Major pharmaceutical companies and record-breaking funding are accelerating breakthroughs in aging biology, with cutting-edge AI technologies playing a central role. Insilico Medicine stands out as a global leader in AI driven drug discovery and aging research, leveraging advanced AI to discover aging biomarkers, therapeutic targets, and novel interventions—achievements showcased at ARDD 2025 alongside top scientists and innovators. Through ongoing collaboration and innovation, Insilico and its partners are paving the way toward the ultimate goal: achieving healthy longevity for everyone on the planet.

Harvard physicists have developed a computational method that can uncover the rules that cells use to self-organize, translating the complex process of cell growth into an optimization problem a computer can solve.

The Global Observing SATellite for Greenhouse gases and Water cycle “IBUKI GW” (GOSAT-GW), developed jointly by the National Institute for Environmental Studies (NIES), the Ministry of the Environment of Japan (MOE), and the Japan Aerospace Exploration Agency (JAXA), was successfully launched on June 29, 2025. The satellite has been in the initial functional verification operations phase. The first observations by the Total Anthropogenic and Natural emissions mapping SpectrOmeter-3 (TANSO-3) onboard this satellite were conducted from July 14 to July 20, 2025, and the proper operation of TANSO-3 was confirmed.

A team from The Hong Kong University of Science and Technology, Fudan University, and the University of Hong Kong has created a new method for generating vectorial holograms—images that encode both intensity and polarization—using ultrathin metasurfaces. Unlike previous approaches, this strategy works under arbitrary incident polarizations and achieves high efficiency, with one device reaching nearly 68 percent. The design combines the Gerchberg–Saxton algorithm with wave decomposition to engineer single-structure meta-atoms that control both phase and polarization. Complex vectorial holographic images are experimentally generated, all within devices less than 200 × 200 μm² and about one-quarter wavelength thick. This breakthrough paves the way for on-chip imaging, optical encryption, and next-generation anticounterfeiting technologies.

Infection control is essential for the success of prosthodontic and oral implant procedures, as microbial contamination can lead to serious complications such as denture stomatitis and peri-implantitis. While synthetic disinfectants like chlorhexidine are commonly used, they may cause side effects including irritation, toxicity, and the development of microbial resistance over time. Natural products derived from plants, animals, and minerals are currently being explored as safer alternatives. Compounds such as epigallocatechin gallate from green tea; eugenol from clove oil; quercetin, thymol, cinnamaldehyde, and flavonoids from propolis; and terpinen-4-ol from tea tree oil have shown strong antimicrobial and anti-biofilm properties. These natural agents are not only effective against harmful oral bacteria but also promote healing, are more biocompatible, environmentally friendly, and are often preferred by patients. However, challenges remain regarding their routine clinical use. The strength and composition of natural agents can vary, and there is a lack of consistent product standards, clinical trials, and comprehensive safety data. Currently, these products are not approved by the U.S. Food and Drug Administration for dental use and are only available as over-the-counter remedies. Production costs and scalability must also be evaluated in comparison with synthetic alternatives. Emerging technologies, such as nanocarriers and targeted delivery systems, are being developed to enhance the effectiveness of natural agents in dental applications. Further clinical research and the establishment of clear regulatory guidelines are necessary to support their integration into clinical practice. Natural disinfectants hold significant potential to become valuable, safe, and sustainable tools for maintaining hygiene in prosthodontics and oral implantology.