Combinatorial peptide synthesis on different solid phases and their thermographic investigation on CO2-binding affinity
Peer-Reviewed Publication
Updates every hour. Last Updated: 30-Oct-2026 14:17 ET (30-Oct-2026 18:17 GMT/UTC)
Researchers used combinatorial solid-phase peptide synthesis and infrared thermography to screen 300 tripeptide sequences for interactions with CO2. Two tripeptides, His(Boc)-Phe-Asn and Phe-Ala-Glu(OtBu), showed reproducible thermal responses after CO2 exposure. The signals were reproduced on glass, functionalised cellulose, and Rink-amide resin, indicating that thermographic screening can help identify peptide candidates for further development as bioinspired CO2-binding materials.
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