New way to destroy a cancer-linked molecule revealed
Peer-Reviewed Publication
Updates every hour. Last Updated: 25-Nov-2025 22:11 ET (26-Nov-2025 03:11 GMT/UTC)
Researchers have created a new type of drug molecule that can precisely destroy TERRA, an RNA molecule that helps certain cancer cells survive. Using advanced “RIBOTAC” technology, their compound finds TERRA inside cells and breaks it down without harming healthy molecules. This discovery could pave the way for a new generation of RNA-based cancer treatments, targeting the disease at its genetic roots rather than just its symptoms.
Looking for new ways to tap into cleaner energy sources? Researchers have come up with a clever method to extract natural gas from underwater hydrate reservoirs by using geothermal energy. Could this be the key to more efficient and affordable energy production? Dive into the full story to find out!
Introducing Genos, an open genomic foundation model for high-quality human genomes across global populations, built to advance understanding of the genome and its diversity. Genos achieves single-nucleotide precision over a context of 1 million bases and uses a Mixture of Experts (MoE) architecture that is practical to deploy and economical to run. We provide two variants, 10B and 1.2B, so teams can match compute and latency needs. Trained on 636 high-quality assemblies representing diverse ancestries, with ~1.6T training tokens for the 1.2B model and ~2.2T for the 10B model, Genos learns the genome itself and generalizes to population-scale analyses. With efficient routing and scalable inference, Genos connects sequence to function and powers tools for discovery and diagnostics, and a complementary 4B multimodal language model pairs genomic signals with text to enable omics-aware reasoning in those tools. Explore code, weights, and docs on GitHub, Hugging Face, ModelScope, and zero2x.
Researchers at the Technical University of Munich (TUM) and TU Darmstadt have studied how text-to-image generators deal with gender stereotypes in various languages. The results show that the models not only reflect gender biases, but also amplify them. The direction and strength of the distortion depends on the language in question.
How can traditional coal-fired power plants adapt to the fluctuating nature of renewable energy? A new pre-gasification burner technology offers a solution, enhancing flexibility and stability even at ultra-low loads. Learn how this innovative approach could transform power plant operations and support a more sustainable energy future.