Dopamine signaling in fruit flies lends new insight into human motivation
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Dec-2025 08:11 ET (24-Dec-2025 13:11 GMT/UTC)
Our brain’s reward system processes and reinforces pleasurable experiences, motivating us to seek out and engage in rewarding activities ranging from eating to social interactions to recreational drug use. Dopamine plays an important role in this process, mediated by the D2 dopamine receptor (D2R). New research published today in Nature Neuroscience finds that the same mechanism that causes drug addiction (desensitization of D2R) also controls the natural devaluation of repeated behaviors (e.g. seeking out the same thrill of going on a rollercoaster for the first time). This is the first natural use found for this mechanism.
Humans bring gender biases to their interactions with Artificial Intelligence (AI), according to new research from Trinity College Dublin and Ludwig-Maximilians Universität (LMU) Munich.
Dance is a form of cultural expression that has endured all of human history, channeling a seemingly innate response to the recognition of sound and rhythm. A team at the University of Tokyo and collaborators demonstrated distinct fMRI activity patterns in the brain related to a specific audience’s level of expertise in dance. The findings were born from recent breakthroughs in dance motion-capture datasets and AI generative models, facilitating a cross-modal study characterizing the art form’s complexity.
Young people who play video games with “gambling-like” elements – such as buying loot boxes or in-game items – are more likely to go on to gamble with real money.