Higher blood sugar levels may lead to negative outcomes for a baby, even when the mother is not diagnosed with gestational diabetes, according to a new study from Penn State researchers.  

Many applications—whether in medicine, biotechnology, or agriculture—require the ability to eliminate unwanted cells, since these can compromise health, reduce productivity, or interfere with desired biological processes. However, doing so without affecting other cells remains a significant challenge. A collaboration of the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, Akribion Therapeutics in Zwingenberg, as well as the University of Utah and Utah State University in the US, has now resulted in a CRISPR-based tool that can target specific cells based on a recognized transcript, opening up numerous potential uses. The findings were published today in the journal Nature.

Scientists have uncovered new evidence that challenges long-held assumptions about the causes of a common type of stroke, offering clues as to why widely used treatments may not work.

Researchers from Queen Mary University of London’s Precision Healthcare University Research Institute and Berlin Institute of Health (BIH) at Charité have published findings from the world’s largest study to date on the genetic regulation of blood proteins.

Researchers analyzing data from the National Institutes of Health’s All of Us Research Program have found that a patient’s step count following surgery is a powerful, objective predictor of recovery, outperforming other metrics such as heart rate variability and self-reported wellness.

A blood test predicts the tumor microenvironment that affects treatment response. Researchers at Stanford Medicine and the Mayo Clinic find nine cellular neighborhoods shared among most cancer cases.

Baylor College of Medicine researchers have found that the human brain is capable of sophisticated language processing while in an unconscious state from general anesthesia. The findings, published in the latest edition of Nature, challenge what we know about the role of consciousness and cognition, and could open new ways of understanding memory, language and brain-computer interfaces.