Identification of an immuno-inflammatory biomarker in the brain supports potentially more effective personalized treatment for major psychiatric disorders
Peer-Reviewed Publication
Updates every hour. Last Updated: 2-Jun-2026 18:15 ET (2-Jun-2026 22:15 GMT/UTC)
Individuals with psychiatric disorders exhibiting seemingly similar symptoms often respond very differently to the same treatment, suggesting that distinct biological processes are at work beneath the surface of similar clinical presentations. Researchers have now identified a distinct immuno-inflammatory biomarker across major psychiatric disorders that can be detected using non-invasive brain imaging. Patients exhibiting this brain signature showed systemic inflammation and poorer response to standard treatments. The findings of the new study in Biological Psychiatry, published by Elsevier, lay the foundation for a biology-augmented diagnostic framework in psychiatry and detail the potential for biomarker-guided, anti-inflammatory precision therapies.
Philip R. Troyk, director of the Pritzker Institute of Biomedical Science and Engineering at Illinois Institute of Technology (Illinois Tech), has been elected a 2025 fellow of the National Academy of Inventors (NAI). The NAI Fellowship is the highest professional distinction awarded solely to inventors, and Troyk is one of 169 inventors from the United States selected for this distinguished honor this year.
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