“Aging brain retains a remarkable capacity for resiliency”
Boston University School of MedicinePeer-Reviewed Publication
Normal aging is characterized by deficits in the cognitive domains of learning, memory and executive function. Specifically, there are age-related changes in recall of information, speed of processing, visuospatial skills and cognitive flexibility. While these age-related changes in cognition, referred to as “normal cognitive aging,” are well-established, the underlying drivers of these changes are not fully understood.
A new study by researchers at Boston University Chobanian & Avedisian School of Medicine has found that a treatment made up of natural particles called extracellular vesicles (EVs), released by stem cells in bone marrow, can slow and even reverse certain aspects of normal age-related memory decline. They showed that tiny vesicles helped maintain memory skills and improved communication between brain areas over a period of two years in an experimental model. According to the researchers, the vesicles contain molecules like proteins, lipids, and RNAs that help to reduce inflammation and support multiple types of brain cells in responding to age-related stress.
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