Frailty fuels gut imbalance and post-surgery gastrointestinal risks
Peer-Reviewed Publication
Updates every hour. Last Updated: 21-Dec-2025 23:11 ET (22-Dec-2025 04:11 GMT/UTC)
A new study reveals that frailty-associated gut dysbiosis significantly elevates the risk of gastrointestinal complications following intracorporeal urinary diversion for bladder cancer. Despite short-term antibiotic prophylaxis, residual intra-abdominal bacteria and fungi—particularly Enterococcus and Enterobacter—were strongly associated with postoperative ileus and infections. The findings underscore frailty as a key determinant of surgical outcomes and point toward microbiota-based management strategies to improve recovery and reduce complications.
Children from less-advantaged socio-economic circumstances have a significantly increased risk of developing asthma. Smoking during pregnancy and breastfeeding are two of the major contributing factors to these inequalities This is stated by a new European study led by the University of Copenhagen. The researchers call for the authorities to support families better.
Increased chromosomal instability impairs oocyte quality, contributing to female reproductive aging. The telomeric DNA damage response (DDR) is essential for genomic stability. Although telomeric DDR has been extensively studied in somatic cells, its role in oocyte aging remains unclear.
The project aims to study the mental health of adolescents aged 14 to 17 living in Spain and to analyse which support networks are important at this stage. To do so, both qualitative and quantitative methodologies were combined, yielding several samples: a representative sample of 806 adolescents nationwide and an additional sample of 228 LGTBI+ adolescents for the survey and 44 LGTBQI+ participants in discussion groups.
The results show that 11.2% of adolescents in the overall sample report feeling very or quite unhappy, and 38.8% indicate that they have experienced loneliness regularly in the past year. Regarding depression, 14% would be experiencing severe episodes, and 6.6% would be in very severe episodes.
Additionally, the study finds that 15.7% of respondents report having attempted suicide, 19.8% have considered it, and 29.3% have engaged in self-harming behaviours in the past year, of which 10.5% report thinking about it frequently.
In reviewing the scientific literature, researchers tend to downplay yoga's effectiveness in enhancing vascular and heart health