Finerenone slows kidney function decline and reduces cardiovascular-kidney risk in non-diabetic chronic kidney disease, major trial shows
Reports and Proceedings
Updates every hour. Last Updated: 30-Oct-2026 02:17 ET (30-Oct-2026 06:17 GMT/UTC)
FIND-CKD is the largest Phase III study to date focused on non-diabetic CKD. The trial enrolled more than 1,500 patients with a range of underlying causes of kidney disease, including hypertension-associated kidney disease and glomerular diseases. Participants were randomised to receive finerenone or placebo in addition to standard of care, including maximally tolerated renin-angiotensin system (RAS)-blocking therapy.
Fatherhood in Black men is associated with lower rates of all-cause mortality by middle age compared to nonfathers, according to the U.S.-based longitudinal study that enrolled Black and White individuals aged 18-30 years at baseline (1985-86). This association was not observed in White fathers in the study. Findings were published in the American Journal of Public Health.
New UC Irvine-led research finds that a father's health before and during parenthood, including obesity, diet, stress and mental health, can influence a child's long-term risk of obesity and related diseases.
Evidence suggests paternal obesity can affect sperm health and biological markers linked to children's metabolism, appetite regulation and disease risk, but some of these changes may be reversible through weight-loss interventions.
Researchers say obesity prevention efforts should more intentionally include fathers through father-friendly health care, mental health support and workplace policies that help parents build healthier family environments.
Nageatte Ibrahim, M.D., an internationally recognized oncology drug development leader and immuno-oncology expert, has been appointed as Research Director of Developmental Therapeutics and Immuno-Oncology for HonorHealth Research Institute.