A new orally taken, gut-based compound developed by scientists from Nanyang Technological University, Singapore, reduces the amount of dietary fat absorbed in the intestines. This differs from most existing weight-loss drugs, which act mainly by suppressing appetite or altering glucose regulation, as well as supplements that claim to boost metabolism to burn more calories. The research is being advanced in collaboration with longevity biomedical biotech firm Aria Bioscience Pte Ltd, to support further development and translation into consumer healthcare products and future therapeutic applications. Obesity has become one of the most pressing global health challenges, affecting more than one billion people worldwide and driving a rise in chronic conditions such as type 2 diabetes, cardiovascular disease and liver disorders. Despite public health efforts, many people continue to struggle with maintaining a healthy weight while consuming a modern diet that is high in fat and sugar. The medical-grade nutraceutical supplement is targeted to reach the market later this year, with upcoming clinical trials to be held. It has also been tested by TUV SUD to be free of microbes and heavy metals.

The 4^th Annual Symposium of Project CHANGE, which is the Kawasaki activity of the national project “COI-NEXT” by Ministry of Education, Culture, Sports, Science and Technology/Japan Science and Technology Agency, will be held at 1:30 pm – 5:10 pm on March 5 (Japan Standard Time) at the Kawasaki Institute of Industrial Promotion Hall. This event will also be streamed online, so please be sure to watch it.

The anti-ulcer activity of Launaea nudicaulis 50% aqueous-alcoholic extract was validated using rat models of aspirin- and pyloric ligation-induced gastric ulcers. At a high dose (400 mg/kg), the extract significantly reduced ulcer index, total acidity, and gastric juice volume while increasing gastric pH, demonstrating efficacy comparable to omeprazole and sucralfate. These findings support its traditional therapeutic value in gastrointestinal disorders.

The precise tuning of magnetic nanoparticle size and spacing directly influences the alignment of intrinsic magnetic moments and magnetic domains, thereby shaping magnetic properties. However, the dynamic evolution mechanisms of magnetic domain configurations in relation to electromagnetic (EM) attenuation behavior remain poorly understood. To address this gap, a thermodynamically controlled periodic coordination strategy is proposed to achieve precise modulation of magnetic nanoparticle spacing. This approach unveils the evolution of magnetic domain configurations, progressing from individual to coupled and ultimately to crosslinked domain configurations. A unique magnetic coupling phenomenon surpasses the Snoek limit in low-frequency range, which is observed through micromagnetic simulation. The crosslinked magnetic configuration achieves effective low-frequency EM wave absorption at 3.68 GHz, encompassing nearly the entire C-band. This exceptional magnetic interaction significantly enhances radar camouflage and thermal insulation properties. Additionally, a robust gradient metamaterial design extends coverage across the full band (2–40 GHz), effectively mitigating the impact of EM pollution on human health and environment. This comprehensive study elucidates the evolution mechanisms of magnetic domain configurations, addresses gaps in dynamic magnetic modulation, and provides novel insights for the development of high-performance, low-frequency EM wave absorption materials.