Deaths due to synthetic opioids nitazenes have likely been underestimated by up to a third.

A new study conducted during the Israel-Hamas war reveals that a teacher's subjective sense of stress and helplessness is a far stronger predictor of burnout than their actual physical exposure to war-related events. By surveying 329 Jewish and Arab educators, the research identified "cognitive reappraisal," the ability to mentally reframe difficult situations, as a vital protective factor that lessens the impact of war exposure on professional exhaustion. These findings suggest that personal resilience can be strengthened through targeted workshops, helping teachers maintain their mental health and efficacy during chronic national crises.

https://doi.org/10.1016/j.apsb.2025.11.025

This new article publication from Acta Pharmaceutica Sinica B, discusses therapeutic drug monitoring of biologics in inflammatory bowel disease.

https://doi.org/10.1016/j.apsb.2025.10.028

This new article publication from Acta Pharmaceutica Sinica B, discusses how structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity.

https://doi.org/10.1016/j.apsb.2025.10.027

This new article publication from Acta Pharmaceutica Sinica B, discusses how palmitoylation of Tfr1 enhances platelet ferroptosis and liver injury in heat stroke.