19-Sep-2025
Coordination clusters as MRI contrast agents
KeAi Communications Co., Ltd.Current clinical protocols predominantly utilize mononuclear gadolinium(III) complexes as contrast agents. Recently, coordination clusters composed of multi-nuclear paramagnetic metal ions have demonstrated promisingly higher relaxation rates as MRI contrast agents and adaptable stability in various solutions, offering promising medical application prospects. This review mainly highlights such advancements, focusing on the influence of ligand selection and structural design on the relaxation rates of metal clusters as MRI contrast agents.
- Journal
- Magnetic Medicine
- Funder
- Medical-Engineering Cross Project of the First Affiliated Hospital of XJTU, Key Scientific and Technological Innovation Team of Shaanxi Province, National Natural Science Foundation of China, Programme of Introducing Talents of Discipline to Universities, Fundamental Research Funds for Central Universities, Key Laboratory Construction Program of Xi'an Municipal Bureau of Science and Technology, “Scientists engineers” Team Building Project of Qin Chuang Yuan in Shaanxi Province of China