Researchers at the University of Tartu showed that large language models can identify, with high accuracy, why patients stop using antidiabetic medications or statins, based on doctors’ electronic clinical notes. The study opens new possibilities for using clinical information that has so far been difficult to analyse in health research.

Cancers caused by mutations in the KRAS gene are challenging to treat, and current KRAS inhibitor therapies can leave behind reversible drug-tolerant persister (DTP) cells that survive therapy, contributing to tumor regrowth and relapse. Researchers from Chiba University found that these surviving cells adapt by reshaping their metabolism. By targeting these metabolic adaptations, the team succeeded in reducing the survival of DTP cells. The findings may help develop therapies to reduce relapse in KRAS-mutant cancers.

Research has revealed how bacteria rely on circadian clocks to control the spread of their multi-cellular colonies.

The findings provide important clues as to how we might improve soil health and plant growth. They may also help to explain how some bacteria spread hospital-acquired infections.

As temperatures soar across the Northern Hemisphere, a free tool lets anyone, anywhere check how dangerous the heat really is for their sport and decide whether it is safe to play.