Giving whole blood or the component parts of blood are equally effective options for paramedics and emergency medical technicians to use in treating patients with severe, traumatic bleeding before arriving at the hospital, according to a large, nationwide trial directed by University of Pittsburgh and UPMC clinicians and scientists.

Pennington Biomedical Research Center, in collaboration with Vanderbilt University Medical Center, has launched a research study, the COACH trial, to test different ways to help children and their families improve their health through lifestyle changes delivered by primary care clinics in communities in Louisiana and Tennessee.

The COACH trial is enrolling 900 children ages 5 to 17 with obesity, which is classified as a BMI at or above the 95th percentile for their age and sex. Patients and their parents are being recruited through urban, suburban and rural doctor’s offices in Tennessee and Louisiana.

Davis Joseph was awarded the 2025 Ciechanover International Biology Award at the Sustainability through Science and Technology Summit 2025 (FLOGEN SIPS 2025) in Cebu, Philippines, for a breakthrough cancer discovery proposing organ-agnostic treatment strategies. His work identifies three universal cancer types based on dysfunctions in p14ARF/p53, DINO lncRNA, and MDM2 activity, and introduces a universal apoptosis network flowsheet built from the analysis of 174 scientific publications. The discovery supports a unified therapeutic framework for treating cancers regardless of the organ in which they originate and is presented as an example of Sustainable Medicine under the FLOGEN Sustainability Framework.