When couples attend relationship counseling, it benefits not only their partnership but also their individual well-being. But which aspects of the training are most influential in this respect? A new study from the University of Illinois Urbana-Champaign examines how a popular intervention program affected individual outcomes such as mental health, sleep, and substance use 

Weight loss is common in Parkinson’s disease, but its biological basis has been unclear. Researchers at Fujita Health University show that this loss reflects reduced body fat, not muscle, along with a shift in energy metabolism. Patients exhibited impaired carbohydrate metabolism, mitochondrial dysfunction, and increased fat breakdown with ketone body production. These changes were most pronounced in thinner patients and those with more advanced disease, revealing a hidden energy crisis in Parkinson’s disease.

A new artificial intelligence-driven pipeline developed in a collaborative research combines protein structure prediction, sequence design, and live-cell screening together to enable rapid conversion of antibody sequences into functional intracellular antibodies (intrabodies) that are stable within living cells. By preserving antigen-binding regions and improving structural stability, the approach overcomes major barriers encountered in intrabody development—emerging as a simpler, more cost-effective tool for diagnostics, imaging, and biomedical research.