This study systematically investigates how chronological age, clinical facial aging features, and perceived age are related in Chinese women aged 15–65 years. By combining expert grading, standardized facial photography, and non-expert age perception assessment, the authors establish a practical method for evaluating perceived age. The findings show that perceived age tends to be slightly older than chronological age and is strongly associated with visible aging features, especially nasolabial folds, marionette folds, facial contour laxity, uneven skin tone, and reduced radiance. This work provides a consumer-relevant tool for anti-aging product evaluation and targeted skincare development.

A new study shows that maintaining favorable lifestyle and health conditions effectively mitigates dementia risk for APOE ε4 noncarriers and heterozygotes, validating population-based public health interventions targeting modifiable risk factors. Conversely, the persistently high risk in homozygotes, regardless of lifestyle, underscores the need for personalized precision prevention alongside these broad public health efforts.